Tony is a NHMRC Principal Research Fellow and Deputy Head Department of Biochemistry at Monash University. He is also Vice President of the Australasian Proteomics Society, a HuPO council member and serves as a Scientific Advisory Board Member of the Human Proteome Project.

He is an Executive Advisory Board member of the journal Proteomics, an Associate Editor of Molecular Immunology and an Editorial Board Member of Molecular and Cellular Proteomics. He consults widely for industry and is on the Scientific Advisory Board of Evaxion Biotech and Bioinformatics Solutions.

His laboratory focusses on how the peptide antigens presented to the immune system, coined the immunopeptidome, is influenced by infection, inflammation and the environment. He has made important contributions to understanding the role of antigen in autoimmune diseases, drug hypersensitivity, cancer and infectious diseases. He is well known for work that has highlighted a role for post-translationally modified antigens in immunity. He has been instrumental in bringing new quantitative tools to immunological studies, in particular the quantitation of the cell surface expression levels of specific HLA-peptide complexes. He is a leader in the field of immunopeptidomics with over 270 related publications.