Dr. Birgit Schilling works at the Buck Institute for Research on Aging in the San Francisco Bay Area since 2000, where she has her own lab as Associate Professor and is Director of the Mass Spectrometry Technology Center. Dr Schilling is interested in translational research and any research that may aim towards therapeutic interventions to improve human aging or disease. Dr. Schilling’s uses modern proteomics technologies, such as data-independent acquisitions to investigate basic mechanisms of aging, as well as using this knowledge to develop biomarkers of aging and disease. Additional key projects in the lab investigate the dynamic role of post-translational modifications (PTMs) during signaling and specifically in the context of metabolic diseases, neurodegenerative diseases, cancer and aging. Combination of data-independent acquisitions with PTM research has allowed to gain better understanding for modification site localization and PTM crosstalk.