HUPO 2022 World Congress

#HUPO 2022 Starts December 4, 2022

Early Career Researchers at HUPO 2022

The HUPO Early Career Researcher (ECR) Initiative was founded in 2015 and has since actively and tirelessly promoted the transmission of HUPO ideals to the next generation of proteomic leaders who are involved in many of the varied HUPO initiatives and activities. Mentoring represents the strongest link between generations of scientists, which is why the ECR is pleased to present a variety of awards and activities in conjunction with HUPO’s annual World Congress.

ECR Manuscript Competition

We are excited to announce the 8th ECR Manuscript Competition at HUPO 2022 to select the “Proteomics Highlight of the Year”. The manuscript competition is a unique opportunity for early career researchers to gain visibility in the proteomics community, as it serves as a platform to highlight the important contributions that postdoctoral fellows, young clinicians and junior faculty members make to the proteomics field. Three finalists were selected to present their manuscripts published during the 2021 and 2022 calendar years in a dedicated plenary session at HUPO2022. An expert committee will evaluate the oral presentations to determine the “Proteomics Highlight of the Year”. The first-place winner will receive a cash prize of $1,000 USD and two runner-ups will each take home $500 USD.

Session Information
Wednesday December 7, 09:15 - 10:00
Chairs: Saeed Seyedmohammad (Cedars-Sinai Medical Center, USA) & Ruth Huttenhain (University of California San Francisco, USA)

Presentations:
Thiol-Cleavable Biotin for Chemical and Enzymatic Biotinylation and Its Application to Mitochondrial TurboID Proteomics
Ling Hao (George Washington University, USA)

The Blood Proteoform Atlas: A reference map of proteoforms in human hematopoietic cells.
Raphael Melani (Northwestern University, USA)

A learned embedding for efficient joint analysis of millions of mass spectra
Wout Bittremieux (University of California San Diego, USA)

This session is sponsored by:

Meet our finalists

Ling Hao
Ling Hao, Ph.D., is an Assistant Professor of Chemistry at the George Washington University in Washington, D.C. She received her PhD from the University of Wisconsin-Madison (mentor: Prof. Lingjun Li) and completed her postdoctoral training at the National Institutes of Health (mentors: Drs. Richard Youle and Michael Ward). Since starting her independent career in 2019, She has received a Ralph E Powe Junior Faculty Enhancement Award from Oak Ridge Associated Universities, a 5-year NIH R01 grant, and a GW UFF grant to support her research in developing mass spectrometry-based bioanalytical chemistry methods to study human brain diseases. She was also recognized as an Emerging Investigator by the Journal of American Society for Mass Spectrometry in 2021. She has co-authored 31 publications, served as a session chair for national and international conferences, a reviewer for 15 research journals, and the guest editor for the Journal of Visualized Experiments for a special method collection “Understanding the Central Nervous System by Mass Spectrometry”. The research in the Hao Lab is focused on developing MS-based proteomics, metabolomics, and proximity labeling techniques to understand mitochondrial and lysosomal biology and decipher molecular mechanisms underlying neurological disorders.

Raphael Melani
Dr. Rafael D. Melani is a Research Assistant Professor in Chemistry at Northwestern University (Evanston, IL - US) and the Associate Director of the Proteomics Center of Excellence. He earned his BS degree in Biology (2010) and a master's degree in Animal Biology (2012) from the University of Brasilia (Brasilia, DF - Brazil). Under Dr. Gilberto Domont's supervision, he got his Ph.D. in Biochemistry (2016) from the Federal University of Rio de Janeiro (Rio de Janeiro, RJ – Brazil). His thesis was awarded the CAPES Thesis Award as one of Brazil's top three best Biochemistry theses in 2016. Rafael's postdoctoral research (2016-2017) was performed in the Proteomics Unit at Federal University of Rio de Janeiro (Rio de Janeiro, Rj – Brazil). In 2017, he joined the Kelleher Research Group and the Proteomics Center of Excellence at Northwestern University. Dr. Melani has extensive experience and training in top-down and bottom-up proteomics, venomics, protein fractionation, mass spectrometry, and native mass spectrometry. His research focuses on improving mass spectrometry-based solutions for the characterization of intact proteoforms in denatured and native conditions and developing translational top-down proteomics methods centered on proteoforms with the capability of linking basic sciences to applied clinical research.

Wout Bittremieux
Dr. Wout Bittremieux is a postdoctoral researcher at the University of California San Diego. His research employs advanced computational techniques to solve fundamental biological questions, by developing algorithmic solutions and machine learning methods for the analysis of mass spectrometry-based proteomics and metabolomics data. He has developed several innovative tools to analyze large mass spectral data volumes, such as the ANN-SoLo tool for extremely fast open modification searching and the GLEAMS deep neural network to efficiently process hundreds of millions of mass spectra. His work is ideally positioned at the intersection of bioinformatics, machine learning, and mass spectrometry.

In 2020, Dr. Bittremieux received the prestigious Postdoctoral Career Development Award from the American Society for Mass Spectrometry, and in 2021 he was named a "Rising Star in Proteomics and Metabolomics" by the Journal of Proteome Research for demonstrating 'incredible originality and promise for the future of proteomics and metabolomics.' Dr. Bittremieux is an avid contributor to the computational mass spectrometry community. He has published widely in internationally recognized scientific journals, is an active member of the European Bioinformatics Community for Mass Spectrometry (EuBIC-MS), and leads the CompMS interest group of the International Society for Computational Biology (ISCB). Furthermore, he has contributed to the development of mass spectrometry data standards defined by the Human Proteome Organization's Proteomics Standards Initiative (PSI) and is an active developer of the Global Natural Products Social Molecular Networking (GNPS) platform, through which his tools reach tens of thousands of monthly users worldwide.

3-Minute Thesis Competition

The HUPO Early Career Researcher (ECR) Initiative in collaboration with the Human Proteome Project has organized a 3-minute thesis competition where candidates will present their research within 3 minutes using one static slide and in a form that can be understood by a general audience. Six candidates have been pre-selected for the final competition, to be held in a parallel session at HUPO 2022 and you are invited to participate. An expert committee as well as the audience will evaluate the presentations to determine the winner and two runner ups. The first-place winner will receive a cash prize of $300 USD and two runner-ups will each take home $100 USD. You won’t want to miss this action!

Session Information
Wednesday December 7, 14:30 - 15:30
Chairs: Maurine Fucito (D'Annunzio University of Chieti Pescara, Italy) and Andreas Hober (KTH Royal Institute of Technology, Sweden)

Meet our Finalists

Xiao Liang (Westlake University, China)

Daniel Menyhart (University of Western Ontario, Canada)

Rethabile Mokoena (CSIR Biosciences/University of the Witwatersrand, South Africa)

Vincent Albrecht (Max Planck Institute of Biochemistry, Germany)

Erin Humphries (Children's Medical Research Institute, Australia)

Jolene Duda (University of Minnesota, USA)

Mentoring Sessions

Three exciting mentoring sessions will be hosted by the HUPO ECR Initiative during HUPO 2022 World Congress. These will provide a forum for mentors and mentees to discuss topics relevant to several areas of building a career. Take a peek below at the roster of session topics and speakers you will meet at these sessions.

Mentoring Session 1: The Art of Job Hunting
Sunday December 4, 16:00 - 17:00
Chairs: Sayantani Chatterjee (Boston University, USA) and Maurine Fucito (D'Annunzio University of Chieti Pescara, Italy)

Speakers:

  • Dr. Benjamin A. Garcia (Washington University in St-Louis, USA)
  • Dr. Morthen Thaysen-Andersen (Macquarie University, Australia)
  • Dr. Claire Eyers (University of Liverpool, UK)

Mentoring Session 2 Imposter Syndrome: What Is It and How Do You Fight It?
Monday December 5, 14:30 - 15:30
Chairs: Daniel Garama (Hudson Institute of Medical Research, Australia) and Lívia Rosa Fernandes (University Sao Paulo, Brazil)

Speakers:

  • Dr. Charles Pineau (University of Rennes, France)
    Dr. Tracy Josephs (Monash University, Australia)
  • Dr. Jennifer Van Eyk (Cedars-Sinai Medical Center, USA)

Mentoring Session 3: Exploring Non-Academic Career Pathways
Tuesday December 6, 16:00 - 17:00
Chairs: Jessica Del Castillo Alferez (Sanquin Research and University of Utrecht, Netherlands) and Omar Mendoza Porras (CSIRO Agriculture and Food, Australia)

Speakers:

  • Dr. Henry Rodriguez (National Institutes of Health, USA)
  • Dr. Christie Hunter (Sciex, USA)
  • Dr. Mark Condina (Mass Dynamics, Australia)
  • Dr. Anjali Seth (Cellenion, France)

ECR Networking Hour (Ticketed Event/Registration Required)

The ECR Networking hour is an entertaining evening for early career researchers from all over the world to meet and mingle. This event will be a fantastic opportunity for early career researchers to network with peers and mentors from all over the world. And senior researchers, you may just find the next superstar to hire!

Event information
The ECR Networking hour will take place at the Aloft Hotel on Monday, December 5 at 19:30 - 22:30.

This event is sponsored by:

Registration
Registration Fees Early Career Researchers: $20 USD
Registration Fees Non Early Career Researchers: $35 USD

To register, please contact hupo2022-registration@icsevents.com.

Visit the ECR at the HUPO Booth in the Exhibit Hall during the HUPO 2022 World Congress

Keep an eye out for the ECR logo and drop by the HUPO booth (#112) at the HUPO 2022 World Congress! This will be a great opportunity to learn about our initiatives, congress activities – or joining our group – we’d love to meet and chat with you! We also have a few surprises in store for you including giveaways and special guests! Stay tuned for more information about these in the coming weeks before the conference!

Poster Competition

All graduate students (Master’s and PhD), as well as postdocs, were invited to participate in the HUPO 2022 poster competition. Finalists in each trainee category (students and postdocs) have been pre-selected based on the quality, novelty, and potential impact of submitted abstracts for the next phase of the competition. The finalists will be visited by evaluators during the poster sessions at HUPO 2022 to ultimately select a winner ($200 USD cash prize) and two runner-ups ($100 USD cash prize) for each category (students and postdocs).

Sponsored by Molecular Omics:

Meet our finalists
Students

  • Max Karlsson (Science for Life Laboratory, Sweden)
    PP02.68 Extending the functional proteomic map by integration of gene expression and biological annotation.
  • Marium Khaleque (The University of Queensland, Australia)
    PP01.156 Regulation of Protein N-linked Glycosylation Site Occupancy.
  • Sebastian Steiner (ETH Zurich, Switzerland)
    PP01.58 Decoding functional surfaceome residing protein interaction communities using CSI-MS.
  • Merve Alp (Max Delbrück Center for Molecular Medicine, Germany)
    PP01.03 Proteomic and Phosphoproteomic Profiling of Head and Neck Cancer Patient-Derived Xenografts Highlights CDK6 as a Potential Drug Target.
  • Tanja Holstein (Federal Institute for Materials Research and Testing, Germany)
    PP01.33 Probability based taxonomic profiling of microbiome samples using PepGM and Unipept.
  • Magdalena Kuras (Lund University, Sweden)
    PP01.111 Proteogenomics linked to histopathology identifies subtypes and progression biomarkers in malignant melanoma.
  • Lilian Heil (University of Washington, USA)
    PP03.34 Microchip CE with integrated solid phase extraction coupled to unit resolution MS enables high sensitivity measurements for low input proteomics.
  • Ludwig Lautenbacher (Technical University of Munich, Germany)
    PP02.69 Deep learning peptide properties for targeted assay and spectral library optimization.
  • Firas Hamood (Technical University of Munich, Germany)
    PP02.60 SIMSI-Transfer: Reduction of missing values in clinical proteomic and phosphoproteomic TMT data using MS2 spectrum clustering.
  • Sophia Laposchan (Technical University of Munich, Germany)
    PP03.168 Characterization of pan-citrullination antibodies for proteome-wide citrullination studies.
  • Wassim Gabriel (Technical University of Munich, Germany)
    PP02.56 Prosit: One model to predict them all.
  • Daniel Menyhart (Western University, Canada)
    PP03.14 Comparison of CX-4945 and SGC-CK2-1 as Inhibitors of CSNK2 using Quantitative Phosphoproteomics.

Postdocs

  • Dr. Claire Martin (Lunenfeld-Tanenbaum Research Institute, Canada)
    PP01.51 Dissecting time and space dynamics within the EGF Receptor signalosome.
  • Dr. Antonella Raffo Romero (Prism Laboratory, France)
    PP03.107 Proteomics and mass spectrometry imaging of three-dimensional cell culture models of breast cancer.
  • Dr. Mehdi Bouhaddou (University of California, Los Angeles, USA)
    PP02.03 Molecular map of SARS-CoV-2 variants of concern: quantitative proteomics, mechanism, and therapy.
  • Dr. Wout Bittremieux (University of California, San Diego, USA)
    PP02.49 Semi-supervised learning for sensitive open modification spectral library searching provides insights in the role of modifications during viral SARS-CoV-2 infection.
  • Dr. Ahrum Son (Scripps Research Institute, USA)
    PP01.57 Protein Footprinting Reveals the Dynamic Conformational Changes of Proteome in Progressing Alzheimer’s Disease.
  • Dr. Christian Hentschker (University of Medicine Greifswald, Germany)
    PP02.08 Comparative analysis of SARS-CoV-2 vector vaccines.
  • Dr. Sophia Escobar-Correas (Commonwealth Scientific and Industrial Research Organization, Australia)
    PP01.14 A classification model for peptides with the potential to trigger coeliac disease.
  • Dr. Seunghyuk Choi (Hanyang University, South Korea)
    PP01.62 pXg: Comprehensive Identification of Noncanonical Peptides from De Novo Peptide Sequencing Using RNA-Seq Reads.
  • Dr. Hsiang-En Hsu (Academia Sinica, Taiwan)
    PP01.100 Measuring Druggable Protein Mutation Abundance towards Precision Oncology by IsoPS DIA-MS.
  • Dr. Leonard Daly (University of Liverpool, United Kingdom)
    PP03.151 Method development for the investigation of the understudied (essential) PTM - Tyrosine-O-Sulfation.
  • Dr. Diana Lashidua Fernández Coto (National Autonomous University of Mexico, Mexico)
    PP03.154 Identification of SIRT3 deacetylation targets in glioblastoma cancer cells with different energy metabolism.
  • Dr. Andreas Zellner (Technical University of Munich, Germany)
    PP03.146 Development of biochemical and analytical pipelines for human plasma peptidomes.

Rising Star Award

This career achievement award is designed to recognize early career trainees who have had an exceptional impact on the proteomics field and community. This impact can take the shape of publications, patents obtained, development of a commercial product, establishment of a course, training program, workshop or any other contributions or service to the field of proteomics.

Meet our first Rising Star

Ling Hao
Ling Hao, Ph.D., is an Assistant Professor of Chemistry at the George Washington University in Washington, D.C. She received her PhD from the University of Wisconsin-Madison (mentor: Prof. Lingjun Li) and completed her postdoctoral training at the National Institutes of Health (mentors: Drs. Richard Youle and Michael Ward). Since starting her independent career in 2019, She has received a Ralph E Powe Junior Faculty Enhancement Award from Oak Ridge Associated Universities, a 5-year NIH R01 grant, and a GW UFF grant to support her research in developing mass spectrometry-based bioanalytical chemistry methods to study human brain diseases. She was also recognized as an Emerging Investigator by the Journal of American Society for Mass Spectrometry in 2021. She has co-authored 31 publications, served as a session chair for national and international conferences, a reviewer for 15 research journals, and the guest editor for the Journal of Visualized Experiments for a special method collection “Understanding the Central Nervous System by Mass Spectrometry”. The research in the Hao Lab is focused on developing MS-based proteomics, metabolomics, and proximity labeling techniques to understand mitochondrial and lysosomal biology and decipher molecular mechanisms underlying neurological disorders.