Early Career Researchers at HUPO 2022
The HUPO Early Career Researcher (ECR) Initiative was founded in 2015 and has since actively and tirelessly promoted the transmission of HUPO ideals to the next generation of proteomic leaders who are involved in many of the varied HUPO initiatives and activities. Mentoring represents the strongest link between generations of scientists, which is why the ECR is pleased to present a variety of awards and activities in conjunction with HUPO’s annual World Congress.
ECR Manuscript Competition
We are excited to announce the 8th ECR Manuscript Competition at HUPO 2022 to select the “Proteomics Highlight of the Year”. The manuscript competition is a unique opportunity for early career researchers to gain visibility in the proteomics community, as it serves as a platform to highlight the important contributions that postdoctoral fellows, young clinicians and junior faculty members make to the proteomics field. Three finalists were selected to present their manuscripts published during the 2021 and 2022 calendar years in a dedicated plenary session at HUPO2022. An expert committee will evaluate the oral presentations to determine the “Proteomics Highlight of the Year”. The first-place winner will receive a cash prize of $1,000 USD and two runner-ups will each take home $500 USD.
Wednesday December 7, 09:15 – 10:00
Chairs: Saeed Seyedmohammad (Cedars-Sinai Medical Center, USA) & Ruth Huttenhain (University of California San Francisco, USA)
Thiol-Cleavable Biotin for Chemical and Enzymatic Biotinylation and Its Application to Mitochondrial TurboID Proteomics
Ling Hao (George Washington University, USA)
The Blood Proteoform Atlas: A reference map of proteoforms in human hematopoietic cells.
Raphael Melani (Northwestern University, USA)
A learned embedding for efficient joint analysis of millions of mass spectra
Wout Bittremieux (University of California San Diego, USA)
This session is sponsored by:
Meet our finalists
Ling Hao, Ph.D., is an Assistant Professor of Chemistry at the George Washington University in Washington, D.C. She received her PhD from the University of Wisconsin-Madison (mentor: Prof. Lingjun Li) and completed her postdoctoral training at the National Institutes of Health (mentors: Drs. Richard Youle and Michael Ward). Since starting her independent career in 2019, She has received a Ralph E Powe Junior Faculty Enhancement Award from Oak Ridge Associated Universities, a 5-year NIH R01 grant, and a GW UFF grant to support her research in developing mass spectrometry-based bioanalytical chemistry methods to study human brain diseases. She was also recognized as an Emerging Investigator by the Journal of American Society for Mass Spectrometry in 2021. She has co-authored 31 publications, served as a session chair for national and international conferences, a reviewer for 15 research journals, and the guest editor for the Journal of Visualized Experiments for a special method collection “Understanding the Central Nervous System by Mass Spectrometry”. The research in the Hao Lab is focused on developing MS-based proteomics, metabolomics, and proximity labeling techniques to understand mitochondrial and lysosomal biology and decipher molecular mechanisms underlying neurological disorders.
Dr. Rafael D. Melani is a Research Assistant Professor in Chemistry at Northwestern University (Evanston, IL – US) and the Associate Director of the Proteomics Center of Excellence. He earned his BS degree in Biology (2010) and a master’s degree in Animal Biology (2012) from the University of Brasilia (Brasilia, DF – Brazil). Under Dr. Gilberto Domont’s supervision, he got his Ph.D. in Biochemistry (2016) from the Federal University of Rio de Janeiro (Rio de Janeiro, RJ – Brazil). His thesis was awarded the CAPES Thesis Award as one of Brazil’s top three best Biochemistry theses in 2016. Rafael’s postdoctoral research (2016-2017) was performed in the Proteomics Unit at Federal University of Rio de Janeiro (Rio de Janeiro, Rj – Brazil). In 2017, he joined the Kelleher Research Group and the Proteomics Center of Excellence at Northwestern University. Dr. Melani has extensive experience and training in top-down and bottom-up proteomics, venomics, protein fractionation, mass spectrometry, and native mass spectrometry. His research focuses on improving mass spectrometry-based solutions for the characterization of intact proteoforms in denatured and native conditions and developing translational top-down proteomics methods centered on proteoforms with the capability of linking basic sciences to applied clinical research.
Dr. Wout Bittremieux is a postdoctoral researcher at the University of California San Diego. His research employs advanced computational techniques to solve fundamental biological questions, by developing algorithmic solutions and machine learning methods for the analysis of mass spectrometry-based proteomics and metabolomics data. He has developed several innovative tools to analyze large mass spectral data volumes, such as the ANN-SoLo tool for extremely fast open modification searching and the GLEAMS deep neural network to efficiently process hundreds of millions of mass spectra. His work is ideally positioned at the intersection of bioinformatics, machine learning, and mass spectrometry.
In 2020, Dr. Bittremieux received the prestigious Postdoctoral Career Development Award from the American Society for Mass Spectrometry, and in 2021 he was named a “Rising Star in Proteomics and Metabolomics” by the Journal of Proteome Research for demonstrating ‘incredible originality and promise for the future of proteomics and metabolomics.’ Dr. Bittremieux is an avid contributor to the computational mass spectrometry community. He has published widely in internationally recognized scientific journals, is an active member of the European Bioinformatics Community for Mass Spectrometry (EuBIC-MS), and leads the CompMS interest group of the International Society for Computational Biology (ISCB). Furthermore, he has contributed to the development of mass spectrometry data standards defined by the Human Proteome Organization’s Proteomics Standards Initiative (PSI) and is an active developer of the Global Natural Products Social Molecular Networking (GNPS) platform, through which his tools reach tens of thousands of monthly users worldwide.